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Gastrin 1 (human),Catalog Number: KS042006,CAS NO.: 10047-33-3

SKU. 172579

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Gastrin-1 is also referred to as Gastrin-17 or “Little Gastrin.” Secretion of gastrin is induced by food intake and causes the release of gastric acid in the stomach. Secreted by the G cells in the gastric mucosa, it is one of the major bioactive forms of gastrin found in tissue and plasma (the other bioactive form is Gastrin-34 or Big Gastrin). Both Gastrin-17 and Gastrin-34 are carboxy-amidated and partially tyrosine sulfated. Binding of Gastrin to the CCK2/gastrin receptor requires carboxy-amidation, however sulfation is not necessary for binding to the receptor. Binding of Gastrin to the CCK2/Gastrin receptors on parietal cells of the stomach causes them to secrete hydrochloric acid (HCl) and stimulates lectin-like protein Reg expression via activation of PKC and RhoA. Gastrin also plays a role in release of Histamine and Pepsinogen.

Catalog Number KS042006
Product Name Gastrin 1 (human)
Sequence Glp-GPWLEEEEEAYGWMDF-NH2
CAS NO. 10047-33-3
price/1mg $100
Purity ≥95% (HPLC)
Molecular Formula C₉₇H₁₂₄N₂₀O₃₁S
Molecular Weight 2098.23
Form Lyophilized
Storage Store at -20°C or -80°C

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