H3K36me3 Acetylation Histone Modification Catalog Number H3112

SKU. 172676

$ 21.12

Stock:: 500 in Stock

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H3-K36me3 Catalog Number H3112 Lyophilized Store At -20°C Or -80°C

Chemically synthesized histone H3 protein, corresponding to residues within 1-135 of human histone H3, trimethylation at K36.

H3K36me3 can bind chromodomain proteins such as MSL3 hMRG15 and scEaf3. It can bind PWWP proteins such as BRPF1 DNMT3A, HDGF2 and Tudor domains such as PHF19 and PHF1. H3K36me3 is required for homologous recombinational repair of DNA damage such as double-strand breaks. The trimethylation is catalyzed by SETD2 methyltransferase. H3K36me3 acts as a mark for HDACs to bind and deacetylate the histone which would prevent run-away transcription. It is associated with both facultative and constitutive heterochromatin.

Catalog Number H3112
Product Name H3-K36me3
Scale 50 μg
Purity ≥95%(HPLC)
price $1056
CAS#. N/A
Sequence ARTKQTARKS TGGKAPRKQL ATKAARKSAP ATGGVKKPHR YRPGTVALRE IRRYQKSTEL LIRKLPFQRL VREIAQDFKT DLRFQSSAVM A
Molecular Formula C₆₇₂H₁₁₅₅N₂₁₅O₁₈₅S₄
Molecular Weight 15314.89
Form Lyophilized
Storage Store at -20°C or -80°C

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